101 - Document - Document and Entity Information link:calculationLink link:presentationLink link:definitionLink 103 - Statement - CONSOLIDATED BALANCE SHEETS link:calculationLink link:presentationLink link:definitionLink 104 - Statement - CONSOLIDATED BALANCE SHEETS (Parenthetical) link:calculationLink link:presentationLink link:definitionLink 105 - Statement - CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS link:calculationLink link:presentationLink link:definitionLink 106 - Statement - CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY link:calculationLink link:presentationLink link:definitionLink 107 - Statement - CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (Parenthetical) link:calculationLink link:presentationLink link:definitionLink 108 - Statement - CONSOLIDATED STATEMENTS OF CASH FLOWS link:calculationLink link:presentationLink link:definitionLink 109 - Disclosure - The Company, Basis of Presentation and Summary of Significant Accounting Policies link:calculationLink link:presentationLink link:definitionLink 110 - Disclosure - Fair Value Measurements link:calculationLink link:presentationLink link:definitionLink 111 - Disclosure - Long-term Debt link:calculationLink link:presentationLink link:definitionLink 112 - Disclosure - Balance Sheet Details link:calculationLink link:presentationLink link:definitionLink 113 - Disclosure - Related Party Transactions link:calculationLink link:presentationLink link:definitionLink 114 - Disclosure - Commitments and Contingencies link:calculationLink link:presentationLink link:definitionLink 115 - Disclosure - Stockholders' Equity link:calculationLink link:presentationLink link:definitionLink 116 - Disclosure - Income Taxes link:calculationLink link:presentationLink link:definitionLink 117 - Disclosure - Employee Savings Plan link:calculationLink link:presentationLink link:definitionLink 118 - Disclosure - Quarterly Financial Data link:calculationLink link:presentationLink link:definitionLink 119 - Disclosure - Subsequent Events link:calculationLink link:presentationLink link:definitionLink 120 - Disclosure - The Company, Basis of Presentation and Summary of Significant Accounting Policies (Policies) link:calculationLink link:presentationLink link:definitionLink 121 - Disclosure - The Company, Basis of Presentation and Summary of Significant Accounting Policies (Tables) link:calculationLink link:presentationLink link:definitionLink 122 - Disclosure - Fair Value Measurements (Tables) link:calculationLink link:presentationLink link:definitionLink 123 - Disclosure - Long-term Debt (Tables) link:calculationLink link:presentationLink link:definitionLink 124 - Disclosure - Balance Sheet Details (Tables) link:calculationLink link:presentationLink link:definitionLink 125 - Disclosure - Commitments and Contingencies (Tables) link:calculationLink link:presentationLink link:definitionLink 126 - Disclosure - Stockholders' Equity (Tables) link:calculationLink link:presentationLink link:definitionLink 127 - Disclosure - Income Taxes (Tables) link:calculationLink link:presentationLink link:definitionLink 128 - Disclosure - Quarterly Financial Data (Tables) link:calculationLink link:presentationLink link:definitionLink 129 - Disclosure - Company Basis of Presentation and Summary of Significant Accounting Policies - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 130 - Disclosure - Weighted-average Assumptions for Stock Option (Detail) link:calculationLink link:presentationLink link:definitionLink 131 - Disclosure - Securities Excluded from Diluted Net Loss Per Common Share (Detail) link:calculationLink link:presentationLink link:definitionLink 132 - Disclosure - Fair Value Measurements on Recurring Basis (Detail) link:calculationLink link:presentationLink link:definitionLink 133 - Disclosure - Fair Value Measurements - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 134 - Disclosure - Long-term Debt - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 135 - Disclosure - Long-term Debt Activity (Detail) link:calculationLink link:presentationLink link:definitionLink 136 - Disclosure - Long-term Debt Activity (Parenthetical) (Detail) link:calculationLink link:presentationLink link:definitionLink 137 - Disclosure - Property and Equipment Net (Detail) link:calculationLink link:presentationLink link:definitionLink 138 - Disclosure - Accrued Expenses (Detail) link:calculationLink link:presentationLink link:definitionLink 139 - Disclosure - Related Party Transactions - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 140 - Disclosure - Commitments and Contingencies - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 141 - Disclosure - Future Minimum Payments (Detail) link:calculationLink link:presentationLink link:definitionLink 142 - Disclosure - Stockholders Equity - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 143 - Disclosure - Changes in Stock Options Outstanding (Detail) link:calculationLink link:presentationLink link:definitionLink 144 - Disclosure - Common Stock Reserved for Future Issuance (Detail) link:calculationLink link:presentationLink link:definitionLink 145 - Disclosure - Deferred Income Taxes (Detail) link:calculationLink link:presentationLink link:definitionLink 146 - Disclosure - Income Taxes - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 147 - Disclosure - Reconciliation of Federal Statutory Income Tax Rate to Effective Income Tax (Detail) link:calculationLink link:presentationLink link:definitionLink 148 - Disclosure - Employee Savings Plan - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 149 - Disclosure - Selected Quarterly Financial Information (Detail) link:calculationLink link:presentationLink link:definitionLink 150 - Disclosure - Subsequent Events - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink